Modeling Disorders of Blood Coagulation in the Zebrafish
نویسندگان
چکیده
منابع مشابه
Disorders of the blood coagulation-fibrinolytic system
Most human cells have no direct contact with the external environment and their living conditions are ensured by blood. An essential criterion for normal blood circulation is the ability of the blood to arrest bleeding at sites of tissue injury and to prevent thrombus formation inside the blood vessels under normal conditions. The balance between these two extreme states is rigorously controlle...
متن کاملCLINICAL CONFERENCE Disorders of Coagulation of Blood
155 PEDIATRICS, January 1958 DR. SCHULMAN: The case we would like to discuss is one chosen for its own intrinsic interest, and also because it provides a good opportunity to illustrate some of our newer know!edge of coagulation in general, and hemophilia in particular. The patient is a 4-year-old boy who was referred to this hospital for investigation of a hemorrhagic diathesis. His birth was n...
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A kinetic Monte Carlo simulation was developed using the deterministic reaction network developed by the Mann laboratory for tissue-factor (TF)-initiated blood coagulation. The model predicted thrombin dynamics in recalcified whole blood (3-fold diluted) pretreated with convulxin (platelet GPVI activator) and picomolar levels of TF (0-14 pM). The model did not accurately predict coagulation tim...
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چکیده یکی از مهمترین دغدغه های بزرگ جوامع بشری، از دیر باز تا کنون که ذهن پژوهشگران و متخصصان بهداشت روانی و اجتماعی و دولتها رابه خود مشغول داشته، مسأله ی بزهکاری می باشد. شناخت کامل پدیده ی بزهکاری و بزهکار، علل وعوامل سقوط یک انسان، چگونگی درمان وی و درنهایت پیشگیری ازبزهکاری ودریک کلام سالم سازی یک جامعه، رسالت عظیم، انسانی ومقدسی می باشد که با بررسی شخصیت مجرم یعنی[ انسانی که تحت شرای...
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ژورنال
عنوان ژورنال: Current Pathobiology Reports
سال: 2015
ISSN: 2167-485X
DOI: 10.1007/s40139-015-0081-3